multidrug resistance genes การใช้

To do this, the doctors proposed inserting a multidrug resistance gene called MDR-1 into the cells of their bone marrow.
In 1992, Fu began working with Elie Hanania, a Palestinian who grew up in Jerusalem, to make the vectors that would be used in studies with the multidrug resistance gene MDR-1.
The hospital would not bill for the cost of the experimental portion of the treatment, under which a multidrug resistance gene would be put into bone marrow to protect patients against the toxic effects of chemotherapy.
A silent mutation in the multidrug resistance gene 1 ( MDR1 ), which codes for a cellular membrane pump that expels drugs from the cell, can slow down translation in a specific location to allow the peptide chain to bend into an unusual conformation.